The HoLEP
Chapter 9

Laser Vaporization of the Prostate: GreenLight PVP and Thulium Laser

Laser vaporization techniques offer a less invasive surgical option for the treatment of benign prostatic hyperplasia compared to enucleation or resection procedures. These methods utilize laser energy to ablate and vaporize the obstructing prostatic tissue, creating an open channel for urine flow. This chapter focuses on the two most prominent laser vaporization technologies: Photoselective Vaporization of the Prostate (PVP) with the GreenLight laser and vaporization techniques using the Thulium laser.

Photoselective Vaporization of the Prostate (PVP) with GreenLight Laser

PVP with the GreenLight laser system has become a widely adopted minimally invasive surgical therapy for BPH. The technology is based on a 532 nm wavelength laser, which is selectively absorbed by hemoglobin. This selective absorption leads to the rapid heating and vaporization of the highly vascularized prostatic tissue, while minimizing damage to surrounding structures. The procedure has evolved through several generations of laser systems, from the original 80W KTP laser to the current 180W XPS system, which offers improved efficiency and vaporization speed.

Surgical Technique of PVP

The PVP procedure is performed transurethrally under general or spinal anesthesia. A laser fiber is passed through a cystoscope, and the laser energy is directed at the obstructing prostatic tissue. The surgeon systematically vaporizes the tissue, typically starting from the bladder neck and working towards the apex, to create a wide and patent prostatic fossa. The excellent hemostatic properties of the GreenLight laser result in a relatively bloodless field and allow for the treatment of patients on anticoagulation therapy in some cases.

Outcomes and Complications of PVP

PVP has been shown to provide significant and durable improvements in urinary symptoms and flow rates. Long-term studies of the 180W XPS system have reported low retreatment rates (approximately 1.1% at 5 years). The procedure is associated with a shorter catheterization time and hospital stay compared to traditional TURP. Complications are generally mild and transient, and may include irritative voiding symptoms, dysuria, and hematuria. The risk of significant bleeding, TUR syndrome, and erectile dysfunction is low.

Thulium Laser Vaporization

The Thulium laser, typically a thulium:YAG (Tm:YAG) laser operating at a wavelength around 2000 nm, is another versatile energy source for the treatment of BPH. The thulium laser energy is highly absorbed by water, allowing for efficient vaporization of prostatic tissue. It can be used in a continuous wave mode, which provides for smooth incision and vaporization.

Surgical Techniques with the Thulium Laser

The Thulium laser can be used for both vaporization and enucleation of the prostate. For vaporization, the technique is similar to PVP, with the laser fiber used to ablate the prostatic tissue. The Thulium laser can also be used for a hybrid procedure known as vapoenucleation (ThuVEP), where the laser is used to incise the tissue planes and enucleate the adenoma, similar to HoLEP.

Outcomes and Complications of Thulium Laser Vaporization

Thulium laser vaporization has demonstrated excellent efficacy and safety in the treatment of BPH. It is a size-independent procedure and is effective for large prostates. The outcomes are comparable to other laser and bipolar techniques, with significant improvements in symptoms and flow rates. The complication profile is also similar, with a low risk of major adverse events.